Setting Up Flask Assuming docker installed in your ubuntu 18.04 instance. Move into your project path. Example : /home/gisak/projects/python/logics/pic_holdr/pic_holdr/pic_flk_holdr Files present within project folder were below. Contents present within requirements.txt file : flask==1.1.1 Contents present within Dockerfile : FROM ubuntu:18.04 MAINTAINER GisakInc 'support@gisakinc.com' RUN apt-get update -y \ apt-get install -y python3-pip python3-dev COPY ./requirements.txt /app/requirements.txt WORKDIR /app RUN pip3 install -r requirements.txt COPY . /app ENTRYPOINT [ "/usr/bin/python3" ] CMD ["base.py"] Contents present within base.py : from flask import Flask app = Flask(__name__) @app.route('/') def hello_world(): return 'Hello, World!' if __name__ == '__main__': app.run(host='0.0.0.0', port=9302) Creating Virtual Environment with python3 : python3.6 -m virtualen